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Walker, B. J. et al. Pilon: an integrated tool for comprehensive microbial var\ iant detection and genome assembly improvement. PLoS One 9, \ne112963 \(2014\).\r:2538)/F 4/H/N/Rect[266.449 632.706 271.708 620.16]/Subtype/Link/Type/Annot>> endobj 5 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd:Table 1 | Global statistics for the Mo17 genome assembly\r:2539)/F 4/H/N/Rect[101.324 590.706 105.835 578.16]/Subtype/Link/Type/Annot>> endobj 6 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd: 23. Jiao, Y. et al. Improved maize reference genome with single-molecule technolo\ gies. Nature 546, 524 527 \(2017\).\r:2540)/F 4/H/N/Rect[225.565 569.706 230.824 557.16]/Subtype/Link/Type/Annot>> endobj 7 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd: 25. Simo, F. A., Waterhouse, R. M., Ioannidis, P., Kriventseva, E. V. & Zdobnov, \ E. M. BUSCO: assessing genome assembly and annotation completeness with single-copy orthologs. Bioinformatics 31, 3210 3212 \ \(2015\).\r:2541)/F 4/H/N/Rect[160.795 548.706 166.054 536.16]/Subtype/Link/Type/Annot>> endobj 8 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd: 26. Kent, W. J. BLAT: the BLAST-like alignment tool. Genome Res. 12, \n656 664 \ \(2002\).\r:2542)/F 4/H/N/Rect[192.792 496.206 198.051 483.66]/Subtype/Link/Type/Annot>> endobj 9 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd: 27. Lu, F. et al. High-resolution genetic mapping of maize pan-genome sequence anc\ hors. Nat. Commun. 6, 6914 \(2015\).\r:2543)/F 4/H/N/Rect[284.259 454.206 289.518 441.66]/Subtype/Link/Type/Annot>> endobj 10 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd: 27. Lu, F. et al. High-resolution genetic mapping of maize pan-genome sequence an\ chors. Nat. Commun. 6, 6914 \(2015\).\r:2544)/F 4/H/N/Rect[187.622 412.206 192.881 399.66]/Subtype/Link/Type/Annot>> endobj 11 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd: 28. Feschotte, C., Jiang, N. & Wessler, S. R. Plant transposable elements: where g\ enetics meets genomics. Nat. Rev. Genet. 3, 329 341 \(2002\).\r:2545)/F 4/H/N/Rect[249.365 349.206 254.57 336.66]/Subtype/Link/Type/Annot>> endobj 12 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd: 29. SanMiguel, P., Gaut, B. S., Tikhonov, A., Nakajima, Y. & Bennetzen, J. L. \nThe\ paleontology of intergene retrotransposons of maize. Nat. Genet. 20, 43 45 \(1998\).\r:2546)/F 4/H/N/Rect[71.963 181.206 77.168 168.66]/Subtype/Link/Type/Annot>> endobj 13 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd: 30. Clark, R. M., Tavar, S. & Doebley, J. Estimating a nucleotide substitution ra\ te for maize from polymorphism at a major domestication locus. Mol. Biol. Evol. 22, 2304 2312 \(2005\).\r:2547)/F 4/H/N/Rect[78.4041 181.206 83.6091 168.66]/Subtype/Link/Type/Annot>> endobj 14 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd: 31. Baucom, R. S. et al. Exceptional diversity, nonrandom distribution, and rapid \ evolution of retroelements in the B73 maize genome. PLoS Genet. 5, e1000732 \(2009\).\r:2548)/F 4/H/N/Rect[102.355 107.706 107.56 95.1602]/Subtype/Link/Type/Annot>> endobj 15 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd: 32. Luo, M. C. et al. Genome sequence of the progenitor of the wheat D genome Aeg\ ilops tauschii. Nature 551, 498 502 \(2017\).\r:2549)/F 4/H/N/Rect[108.796 107.706 114.001 95.1602]/Subtype/Link/Type/Annot>> endobj 16 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd: 23. Jiao, Y. et al. Improved maize reference genome with single-molecule technol\ ogies. Nature 546, 524 527 \(2017\).\r:2550)/F 4/H/N/Rect[277.452 65.7059 282.386 53.1602]/Subtype/Link/Type/Annot>> endobj 17 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd: 33. Law, M. et al. Automated update, revision, and quality control of the maize ge\ nome annotations using MAKER-P improves the B73 RefGen_v3 gene models and identifies new genes. Plant Physiol. 167, 25 39 \(\ 2015\).\r:2551)/F 4/H/N/Rect[283.487 65.7059 288.421 53.1602]/Subtype/Link/Type/Annot>> endobj 18 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd: 16. Hirsch, C. N. et al. Draft assembly of elite inbred line PH207 provides insig\ hts into genomic and transcriptome diversity in maize. Plant Cell 28, 2700 2714 \(2016\).\r:2552)/F 4/H/N/Rect[111.902 55.2059 117.107 42.6602]/Subtype/Link/Type/Annot>> endobj 19 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd:Fig. 1 | Genomic landscape between B73 and Mo17 genomes. a, Distribution of s\ ubgenome 1 \(red\) and subgenome 2 \(yellow\) in the B73 and Mo17 genomes. Gray indicates regions without assigned subgenome infor\ mation. b,c, Transposable-elemen:2553)/F 4/H/N/Rect[337.916 485.706 342.38 473.16]/Subtype/Link/Type/Annot>> endobj 20 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd: 34. Kurtz, S. et al. Versatile and open software for comparing large genomes. Gen\ ome Biol. 5, R12 \(2004\).\r:2554)/F 4/H/N/Rect[375.044 443.706 380.249 431.16]/Subtype/Link/Type/Annot>> endobj 21 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd: 35. Brunner, S., Fengler, K., Morgante, M., Tingey, S. & Rafalski, A. Evolution \no\ f DNA sequence nonhomologies among maize inbreds. Plant Cell 17, 343 360 \(2005\).\r:2555)/F 4/H/N/Rect[364.727 380.706 369.932 368.16]/Subtype/Link/Type/Annot>> endobj 22 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd:Fig. 1 | Genomic landscape between B73 and Mo17 genomes. a, Distribution of \ subgenome 1 \(red\) and subgenome 2 \(yellow\) in the B73 and Mo17 genomes. Gray indicates regions without assigned subgenome info\ rmation. b,c, Transposable-eleme:2556)/F 4/H/N/Rect[542.954 233.706 547.418 221.16]/Subtype/Link/Type/Annot>> endobj 23 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd: 3. Springer, N. M. et al. Maize inbreds exhibit high levels of copy number variati\ on \(CNV\) and presence/absence variation \(PAV\) in genome content. 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Maize HapMap2 identifies extant variation from a genome in \ flux. Nat. Genet. 44, 803 807 \(2012\).\r:2561)/F 4/H/N/Rect[99.7245 160.206 104.929 147.66]/Subtype/Link/Type/Annot>> endobj 39 0 obj <>/BS<>/Border[0 0 0]/Dest(SpringerNature_NatGenet_182.indd:Fig. 1 | Genomic landscape between B73 and Mo17 genomes. a, Distribution of\ subgenome 1 \(red\) and subgenome 2 \(yellow\) in the B73 and Mo17 genomes. 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Nonsyntenic genes drive RTCS-dependent regulation of the embryo\ transcriptome during formation of seminal root primordia in maize \(Zea mays L.\). J. Exp. 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